Assessment of myocardial reperfusion by intraveneous myocardial contrast echocardiography and coronary flow reserve after primary percutaneous transluminal coronary angiography in patients with acute myocardial infarction
| العنوان: | Assessment of myocardial reperfusion by intraveneous myocardial contrast echocardiography and coronary flow reserve after primary percutaneous transluminal coronary angiography in patients with acute myocardial infarction |
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| المؤلفون: | Andreas Franke, Jürgen vom Dahl, Peter Hanrath, Rainer Hoffmann, Uwe Janssens, Otto Kamp, Paolo Voci, Gertjan Tj. Sieswerda, Carel C. de Cock, Harald P. Kühl, Wolfgang Lepper, Cees A. Visser |
| المساهمون: | VU University medical center |
| المصدر: | Circulation, 101(20), 2368-2374. Lippincott Williams and Wilkins Lepper, W, Kamp, O, Franke, A, de Cock, C C & Kuhl, H P 2000, ' Assessment of myocardial reperfusion by intraveneous myocardial contrast echocardiography and coronary flow reserve after primary percutaneous transluminal coronary angiography in patients with acute myocardial infarction. ', Circulation, vol. 101, no. 20, pp. 2368-2374 . https://doi.org/10.1161/01.cir.101.20.2368 |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | medicine.medical_specialty, Percutaneous, Myocardial reperfusion, business.industry, Coronary flow reserve, Blood flow, medicine.disease, Microcirculation, Coronary circulation, medicine.anatomical_structure, Physiology (medical), Internal medicine, medicine, Cardiology, cardiovascular diseases, Myocardial infarction, Cardiology and Cardiovascular Medicine, business, Perfusion |
| الوصف: | Background —This study investigated whether the extent of perfusion defect determined by intravenous myocardial contrast echocardiography (MCE) in patients with acute myocardial infarction (AMI) treated by primary percutaneous transluminal coronary angioplasty (PTCA) relates to coronary flow reserve (CRF) for assessment of myocardial reperfusion and is predictive for left ventricular recovery. Methods and Results —Twenty-five patients with first AMI underwent intravenous MCE with NC100100 with intermittent harmonic imaging before PTCA and after 24 hours. MCE before PTCA defined the risk region and MCE at 24 hours the “no-reflow” region. The no-reflow region divided by the risk region determined the ratio to the risk region. CFR was assessed immediately after PTCA and 24 hours later. Left ventricular wall motion score indexes were calculated before PTCA and after 4 weeks. CFR at 24 hours defined a recovery (CFR ≥1.6; n=17) and a nonrecovery group (CFR P =0.009). A ratio to the risk region of ≤50% defined an MCE reperfusion group. It was associated with improvement of CFR from 1.67±0.47 at baseline to 2.15±0.53 at 24 hours ( P P Conclusions —Intravenous MCE can be used to define perfusion defects after AMI. Assessment of microcirculation by MCE corresponds to evaluation by CFR. Serial intravenous MCE has the potential to identify patients likely to have improved left ventricular function after AMI. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0009-7322 |
| DOI: | 10.1161/01.cir.101.20.2368 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b83d13a0c31fa1f33b26b662deca9c0 https://doi.org/10.1161/01.cir.101.20.2368 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0b83d13a0c31fa1f33b26b662deca9c0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00097322 |
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| DOI: | 10.1161/01.cir.101.20.2368 |