ent-Abietane diterpenoids from Isodon xerophilus
| العنوان: | ent-Abietane diterpenoids from Isodon xerophilus |
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| المؤلفون: | Li Mei Li, Jian-Xin Pu, Han-Dong Sun, Wei Lie Xiao |
| المصدر: | Archives of Pharmacal Research. 34:875-879 |
| بيانات النشر: | Springer Science and Business Media LLC, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Stereochemistry, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Drug Discovery, otorhinolaryngologic diseases, medicine, Humans, Isodon xerophilus, Abietane, biology, Plant Extracts, Spectrum Analysis, Organic Chemistry, Human cell, biology.organism_classification, medicine.disease, digestive system diseases, Plant Leaves, chemistry, Chemical constituents, Abietanes, Isodon, Molecular Medicine, Lamiaceae, Drug Screening Assays, Antitumor, Stomach Adenocarcinoma, K562 cells, Chronic myelogenous leukemia |
| الوصف: | Three new ent-abietanoids, named xerophilusins XIV-XVI, and four known analogues, as well as four known chemical constituents were isolated from the leaves of Isodon xerophilus. Their structures were elucidated by extensive spectroscopic studies, and comparison with literature data. In addition, the cytotoxic activity of the ent-abietanoids against chronic myelogenous leukemia (K562), stomach adenocarcinoma (MKN45), and hepatocellular carcinoma (HepG2) human cell lines was investigated and no activities were observed. |
| تدمد: | 1976-3786 0253-6269 |
| DOI: | 10.1007/s12272-011-0602-5 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e8abaf6e5b3048d6c521d679d3e0ec https://doi.org/10.1007/s12272-011-0602-5 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....09e8abaf6e5b3048d6c521d679d3e0ec |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19763786 02536269 |
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| DOI: | 10.1007/s12272-011-0602-5 |