Endothelium may play a part in the pathogenesis of longstanding psoriatic arthritis (PsA),1 whereas a higher vascularisation and a less intense adhesion molecule expression have been found in PsA synovial membrane compared with rheumatoid arthritis.2 Some proinflammatory molecules, such as tumour necrosis factors (TNFs), can induce synovial endothelial cells and fibroblast-like synoviocytes to express adhesion molecules.3, 4 In two groups of patients with PsA—eight patients with synovitis of 1 year—we studied the expression and pattern of the synovial distribution of endothelial leucocyte adhesion molecule-1 (ELAM-1 or E-selectin) (CD62E), intercellular adhesion molecule-1 (ICAM-1) (CD54), vascular cell adhesion molecule-1 (VCAM-1) (CD106) (Immunotech, Marseille, France), and of TNFα and TNFβ cytokines (Chemicon International, Temecula, CA, USA) using a standard three stage immunoperoxidase labelling technique (LAB VISION, Fremont, …