التفاصيل البيبلوغرافية
| العنوان: |
Extracorporeal CO2 removal and O2 transfer: A review of the concept, improvements and future development |
| المؤلفون: |
J. Pernechele, T. Tenaglia, Pierpaolo Terragni, G. Maiolo, Vito Marco Ranieri |
| المساهمون: |
Terragni, P.P., Maiolo, G., Tenaglia, T., Pernechele, J., Ranieri, V.M. |
| سنة النشر: |
2011 |
| مصطلحات موضوعية: |
lung vascular resistance, metabolic disorder, ARDS, blood carbon dioxide tension, heart output, multiple organ failure, medicine.medical_treatment, heparin, Critical Care and Intensive Care Medicine, heart lung machine, low drug dose, compartment syndrome, lung gas exchange, heart contraction, oxygen, acute respiratory failure, carbon dioxide tension, Acute respiratory distress syndrome (ARDS), randomized controlled trial (topic), Tidal volume, systemic circulation, lung infection, pH, hematoma, tidal volume, artificial ventilation, adult respiratory distress syndrome, neurologic disease, oxygen consumption, oxygen dissociation curve, extracorporeal carbon dioxide removal, medicine.anatomical_structure, priority journal, Anesthesia, mean arterial pressure, arterial pressure, extracorporeal circulation, catheter thrombosi, overall survival, intracranial pressure, review, ExtraCorporeal membrane oxygenation (ECMO), blood transfusion, lung blood flow, Extracorporeal, leg ischemia, ventilator induced lung injury, Co2 removal, medicine, Extracorporeal membrane oxygenation, tissue oxygenation, human, blood pump, Lung, hypoxemia, nonhuman, extracorporeal oxygenation, business.industry, carbon dioxide, hypercapnia, Oxygenation, medicine.disease, bleeding, mortality, hyperinflation, interventional lung assist, Respiratory acidosis, lung barotrauma, Anesthesiology and Pain Medicine, ExtraCorporeal CO2Removal (ECCO2R), lung ventilation, inflammation, aneurysm, respiratory acidosi, business |
| الوصف: |
Since the 70s, the extracorporeal carbon dioxide removal concept played a role in adjusting respiratory acidosis associated with Tidal Volume reduction in protective ventilation settings.Kolobow and Gattinoni in 1977 were the first in introducing extracorporeal support, with the intent to separate carbon dioxide removal from oxygen uptake: carbon dioxide was removed by a pump-driven modified ECMO with veno-venous bypass, while oxygenation was accomplished by high levels of PEEP, applying only a few ventilator breaths at low volumes and low peak inspiratory pressures (" lung rest" ) to prevent damage of the compromised lungs.Nevertheless extracorporeal support was restricted to controlled clinical trials because of the high incidence of serious complications like hemorrhage, hemolysis and neurological impairments.Technological improvement led to the implementation of different devices less invasive for the patient and less complex for clinician (however unable to transfer oxygen): the interventional Lung Assist (iLA) and the Veno-venous ECCO2R, which brought back attention to the CO2 removal concept.Is foreseeable the future development of more efficient devices capable of removing a substantial amount of carbon dioxide allowing a more protective ventilation. This would embody the modern mechanical ventilation philosophy: avoid tracheal tubes, minimize sedation, prevent VILI and hospital acquired infections. © 2011 Elsevier Ltd. |
| وصف الملف: |
STAMPA |
| اللغة: |
English |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084187ffd0e84b7d8480d01afb2b317c
http://hdl.handle.net/11585/670537 |
| Rights: |
CLOSED |
| رقم الانضمام: |
edsair.doi.dedup.....084187ffd0e84b7d8480d01afb2b317c |
| قاعدة البيانات: |
OpenAIRE |