Repeat Hepatectomy After Major Hepatectomy for Colorectal Liver Metastases
| العنوان: | Repeat Hepatectomy After Major Hepatectomy for Colorectal Liver Metastases |
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| المؤلفون: | Masatoshi Makuuchi, Kei Shimada, Yoshikazu Maruyama, Takuya Hashimoto, Akinori Miyata, Takeshi Takamoto |
| المصدر: | Journal of Gastrointestinal Surgery. 24:380-387 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, Reoperation, medicine.medical_specialty, Liver tumor, medicine.medical_treatment, Repeat hepatectomy, 030230 surgery, Gastroenterology, Lesion, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Overall survival, Hepatectomy, Humans, In patient, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Liver Neoplasms, Significant difference, Middle Aged, medicine.disease, Tumor Burden, Survival Rate, 030220 oncology & carcinogenesis, Feasibility Studies, Female, Surgery, Neoplasm Recurrence, Local, medicine.symptom, Colorectal Neoplasms, business, Major hepatectomy |
| الوصف: | This study assessed predictors of survival after repeat hepatectomy and the feasibility of a repeat hepatectomy after a major hepatectomy in the patients with colorectal liver metastases (CLM). More than half of all patients who receive a curative initial hepatectomy for CLM develop hepatic recurrence, and aggressive indications for a repeat hepatectomy can improve the outcome in selected patients. However, the feasibility of repeat hepatectomy after major hepatectomy remains uncertain, and optimal selection criteria for repeat hepatectomy have not yet been established. Data were collected retrospectively on 296 CLM patients who underwent an initial curative hepatectomy between 2007 and 2017 at our institution. The postoperative outcomes of patients undergoing a repeat hepatectomy after major hepatectomy were assessed, and independent predictors of survival were investigated. After a median follow-up period of 32 months, 247 patients (83%) developed disease recurrence and 122 patients (49%) underwent repeat hepatectomy. The 5-year overall survival (OS) was significantly higher in patients who underwent a repeat hepatectomy than in those who did not receive repeat hepatectomy (51% vs. 19%, respectively; P |
| تدمد: | 1873-4626 1091-255X |
| DOI: | 10.1007/s11605-019-04154-8 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036ce863240882ed7995bd2b8cdf82c3 https://doi.org/10.1007/s11605-019-04154-8 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....036ce863240882ed7995bd2b8cdf82c3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18734626 1091255X |
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| DOI: | 10.1007/s11605-019-04154-8 |