Neurological Deficits among Beta-Thalassemia Patients and its Possible Therapeutic Intervention : A Comprehensive Review
| العنوان: | Neurological Deficits among Beta-Thalassemia Patients and its Possible Therapeutic Intervention : A Comprehensive Review |
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| المؤلفون: | Rimsha Khan, Fahad Hassan Shah, Affifa Tahir Khan, Abid Ali Khan, Saad Salman, Syed Turab Ali Shah, Jawaria Idrees |
| المصدر: | Journal of the Dow University of Health Sciences, Vol 14, Iss 2, Pp 83-90 (2020) |
| بيانات النشر: | Dow University of Health Sciences, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Pediatrics, medicine.medical_specialty, beta thalassemia, evoked potential, treatment, business.industry, lcsh:R, Neurotoxicity, Beta thalassemia, lcsh:Medicine, Disease, medicine.disease, extramedullary hematopoiesis, Health Professions (miscellaneous), Extramedullary hematopoiesis, Intervention (counseling), medicine, neuropathy, medicine.symptom, Evoked potential, Myopathy, business, Stroke, neurological deficits, cognitive impairment |
| الوصف: | Beta-thalassemia is a genetico-haematological disorder that affects the integrity, structure, and survival of red blood cells due to deleterious mutation in the β-globulin chain of hemoglobin. Other than blood disorder, this condition gives rise to numerous neurological and haematophysiological conditions which have not been fully discussed yet. These conditions include extramedullary hematopoiesis, evoked potential (Sensory, Auditory and Visual), neuropathy and myopathy and predisposition to the hypercoagulable state leading to stroke. Moreover, most opted therapy to alleviate this condition intrigue neurotoxicity that requires clinician's round the clock attention. Beta thalassemia remains an incurable disease, and various therapies have been introduced to fulfill the body's blood requirement. But this condition implicitly gives rise to a damaging range of symptoms that cannot be overlooked. Therefore, our review encompasses all those anomalies associated with beta-thalassemia and its probable curative therapy. Keywords: Beta thalassemia, Neurological deficits, Cognitive impairment, Extramedullary hematopoiesis, Evoked potential, Neuropathy. |
| اللغة: | English |
| تدمد: | 2410-2180 1995-2198 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035e6093f0525cc36613691236394e19 http://www.jduhs.com/index.php/jduhs/article/view/831 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....035e6093f0525cc36613691236394e19 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 24102180 19952198 |
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