Pre-diagnostic breastfeeding, adiposity, and mortality among parous Hispanic and non-Hispanic white women with invasive breast cancer: the Breast Cancer Health Disparities Study
| العنوان: | Pre-diagnostic breastfeeding, adiposity, and mortality among parous Hispanic and non-Hispanic white women with invasive breast cancer: the Breast Cancer Health Disparities Study |
|---|---|
| المؤلفون: | Avonne E. Connor, Roger K. Wolff, Lisa M. Hines, Stephanie D. Boone, Esther M. John, Martha L. Slattery, Richard N. Baumgartner, Kathy B. Baumgartner, Kala Visvanathan |
| المصدر: | Breast Cancer Research and Treatment. 161:321-331 |
| بيانات النشر: | Springer Science and Business Media LLC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Adult, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Breastfeeding, Breast Neoplasms, Lower risk, Article, White People, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Risk Factors, Cause of Death, Risk of mortality, Humans, Medicine, Neoplasm Invasiveness, Healthcare Disparities, Adiposity, Aged, Neoplasm Staging, Aged, 80 and over, Gynecology, business.industry, Hazard ratio, Hispanic or Latino, Middle Aged, medicine.disease, Parity, Breast Feeding, 030104 developmental biology, Oncology, Case-Control Studies, Population Surveillance, 030220 oncology & carcinogenesis, Population study, Female, business, Body mass index, Breast feeding, SEER Program, Demography |
| الوصف: | U.S. Hispanic women have high rates of parity, breastfeeding, and obesity. It is unclear whether these reproductive factors are associated with breast cancer (BC) mortality. We examined the associations between breastfeeding, parity, adiposity and BC-specific and overall mortality in Hispanic and non-Hispanic white (NHW) BC cases. The study population included 2921 parous women (1477 Hispanics, 1444 NHWs) from the Breast Cancer Health Disparities Study with invasive BC diagnosed between 1995 and 2004. Information on reproductive history and lifestyle factors was collected by in-person interview. Overall and stratified Cox proportional hazard regression models by ethnicity, parity, and body mass index (BMI) at age 30 years were used to calculate hazard ratios (HR) and 95% confidence intervals (CI). After a median follow-up time of 11.2 years, a total of 679 deaths occurred. Pre-diagnostic breastfeeding was associated with a 16% reduction in mortality (HR 0.84; 95% 0.72–0.99) irrespective of ethnicity. Parity significantly modified the association between breastfeeding duration and mortality (p interaction = 0.05), with longer breastfeeding duration associated with lower risk among women who had ≤2 births (p trend = 0.02). Breastfeeding duration was associated with reduced risk of both BC-specific and overall mortality among women with BMI |
| تدمد: | 1573-7217 0167-6806 |
| DOI: | 10.1007/s10549-016-4048-9 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0308141d6d26a207d504e589dbd36362 https://doi.org/10.1007/s10549-016-4048-9 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0308141d6d26a207d504e589dbd36362 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15737217 01676806 |
|---|---|
| DOI: | 10.1007/s10549-016-4048-9 |