Re-examining the role and random nature of phase variation
| العنوان: | Re-examining the role and random nature of phase variation |
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| المؤلفون: | Marjan W. van der Woude |
| المصدر: | FEMS Microbiology Letters. 254:190-197 |
| بيانات النشر: | Oxford University Press (OUP), 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | Genetics, Phase variation, Study phase, Bacteria, Process (engineering), Stochastic process, Gene Expression Regulation, Bacterial, Biology, Adaptation, Physiological, Microbiology, Phenotype, Variation (linguistics), Bacterial Proteins, Evolutionary biology, Biofilms, Host organism, Animals, Humans, Adaptation, Molecular Biology |
| الوصف: | Phase variation in bacteria is often considered a random process that has evolved to facilitate immune evasion in a host. Here, alternative biological roles for this process are presented and discussed, incorporating recent studies on nonpathogenic and commensal bacterial species. Furthermore, the integration of phase variation into bacterial regulatory networks and the relevance of this for considering phase variation as a random process are reviewed. Novel approaches are needed to study phase variation and its biological roles, but the insights obtained can contribute significantly to our understanding of the dynamic behaviour of bacterial populations and their interactions with the environment. |
| تدمد: | 1574-6968 0378-1097 |
| DOI: | 10.1111/j.1574-6968.2005.00038.x |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010ce31c9cc48d94ce7bd099d5ded2c5 https://doi.org/10.1111/j.1574-6968.2005.00038.x |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....010ce31c9cc48d94ce7bd099d5ded2c5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15746968 03781097 |
|---|---|
| DOI: | 10.1111/j.1574-6968.2005.00038.x |