The histopathology of alopecia areata in vertical and horizontal sections
| العنوان: | The histopathology of alopecia areata in vertical and horizontal sections |
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| المؤلفون: | David A. Whiting |
| المصدر: | Dermatologic Therapy. 14:297-305 |
| بيانات النشر: | Hindawi Limited, 2001. |
| سنة النشر: | 2001 |
| مصطلحات موضوعية: | medicine.medical_specialty, Pathology, integumentary system, medicine.diagnostic_test, Pigment incontinence, business.industry, Common disease, Dermatology, General Medicine, Alopecia areata, medicine.disease, medicine.anatomical_structure, Scalp, Follicular phase, Biopsy, Vellus hair, medicine, Histopathology, business |
| الوصف: | Alopecia areata (AA) is a relatively common disease affecting 1.7% of Americans by the age of 50 years. The diagnosis is usually made on clinical grounds. In some cases the diagnosis is elusive and biopsies are necessary. In other cases biopsies are useful from a prognostic point of view to determine whether there are enough follicles left for possible future regrowth. In view of the active research being conducted into AA, biopsies provide valuable material for further investigation. The diagnosis of AA is improved by the use of horizontal sections in addition to or instead of vertical sections of scalp biopsies. The histopathologic features favoring the diagnosis of AA include peribulbar and intrabulbar mononuclear infiltrates, degenerative changes in the hair matrix, decreased numbers of terminal anagen follicles, increased numbers of terminal catagen and telogen follicles, an increased number of follicular stelae, an increased number of miniaturized vellus hair follicles, and pigment incontinence of hair bulbs and follicular stelae. Follicular counts with horizontal sections are particularly helpful in making the diagnosis of AA when the biopsy has been taken between acute episodes and the characteristic peribulbar inflammatory infiltrate is absent. |
| تدمد: | 1529-8019 1396-0296 |
| DOI: | 10.1046/j.1529-8019.2001.01037.x |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ff0714820e2a2de0bb748ee831da304f https://doi.org/10.1046/j.1529-8019.2001.01037.x |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........ff0714820e2a2de0bb748ee831da304f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15298019 13960296 |
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| DOI: | 10.1046/j.1529-8019.2001.01037.x |