ChemInform Abstract: Palladium-Catalyzed [2 + 1] Cycloadditions Affording Vinylidenecyclopropanes as Precursors of 7-Membered Carbocycles

التفاصيل البيبلوغرافية
العنوان: ChemInform Abstract: Palladium-Catalyzed [2 + 1] Cycloadditions Affording Vinylidenecyclopropanes as Precursors of 7-Membered Carbocycles
المؤلفون: Aymeric Lepronier, Gérard Buono, Hervé Clavier, Thierry Achard, Alphonse Tenaglia, Laurent Giordano
المصدر: ChemInform. 47
بيانات النشر: Wiley, 2016.
سنة النشر: 2016
مصطلحات موضوعية: chemistry.chemical_compound, Denticity, Chemistry, Propargyl, chemistry.chemical_element, General Medicine, Cleavage (embryo), Medicinal chemistry, Cycloaddition, Phosphine, Catalysis, Palladium
الوصف: Palladium(II) acetate in association with secondary phosphine oxides provides an efficient catalytic system for [2+1] cycloadditions starting from oxanorbornene derivatives and tertiary propargyl esters giving rise to vinylidenecyclopropanes. This reaction is specific to bidentate phosphinito-phosphinous acid ligands generated from secondary phosphine oxides. The [2+1] cycloaddition was found broad in scope with a high tolerance to various functional groups. Moreover, vinylidenecyclopropanes were straightforwardly converted into oxabicyclo[3.2.1]oct-2-ene derivatives through a palladium-catalyzed ring-expansion. Finally, the oxa bridge cleavage of oxatricyclic compounds allows the obtention of functionalized 7-membered carbocycles.
تدمد: 0931-7597
DOI: 10.1002/chin.201627120
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd3955ab2df99ab1bdc90a29218f19df
https://doi.org/10.1002/chin.201627120
Rights: CLOSED
رقم الانضمام: edsair.doi...........fd3955ab2df99ab1bdc90a29218f19df
قاعدة البيانات: OpenAIRE
الوصف
تدمد:09317597
DOI:10.1002/chin.201627120