Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
| العنوان: | Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design |
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| المؤلفون: | Jale Karolyi-Oezguer, Renate Schnitzer, Heribert Arnhof, Emelyne Diers, Andreas Zoephel, Harald Weinstabl, Bernadette Sharps, Darryl B. McConnell, Katharina Ehrenhöfer-Wölfer, Peter Ettmayer, David Zollman, Joerg Rinnenthal, Guido Boehmelt, Michael J. Roy, Meng-Ying Wu, Alessio Ciulli, Thomas Gerstberger, Klaus Rumpel, William Farnaby, Carina Riedmueller, Alexander Weiss-Puxbaum, Nicole Trainor, Peter Greb, Mark Pearson, Johannes Wachter, Michael Galant, Steffen Steurer, Tom Owen-Hughes, Oliver Petermann, Simon Wöhrle, Manfred Koegl, Nicola Wiechens, Elisabeth Traxler, Gerd Bader, Teresa Gmaschitz, Christian Dank, Claire Whitworth |
| المصدر: | Nature Chemical Biology. 15:846-846 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0303 health sciences, Chemistry, DNA repair, 030302 biochemistry & molecular biology, Cell Biology, Chromatin remodeling, Cell biology, Bromodomain, Chromatin, 03 medical and health sciences, chemistry.chemical_compound, Transcription (biology), SMARCA4, Nucleosome, Molecular Biology, DNA, 030304 developmental biology |
| الوصف: | In the version of this article originally published, several lines of text in the last paragraph of the right column on page 1 of the PDF were transposed into the bottom paragraph of the left column. The affected text of the left column should read "The ATP-dependent activities of the BAF (SWI/SNF) chromatin remodeling complexes affect the positioning of nucleosomes on DNA and thereby many cellular processes related to chromatin structure, including transcription, DNA repair and decatenation of chromosomes during mitosis12,13." The affected text of the right column should read "SMARCA2/4BD inhibitors are thus precluded from use for the treatment of SMARCA4 mutant cancers but could provide attractive ligands for PROTAC conjugation. Small molecules binding to other bromodomains have been successfully converted into PROTACs by conjugating them with structures capable of binding to the E3 ligases von Hippel-Lindau (VHL) or cereblon5,6,10,11,25,26,27." The errors have been corrected in the PDF version of the paper. |
| تدمد: | 1552-4469 1552-4450 |
| DOI: | 10.1038/s41589-019-0329-z |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::f7486b9d8ad9fe9437d9ccce229082c6 https://doi.org/10.1038/s41589-019-0329-z |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........f7486b9d8ad9fe9437d9ccce229082c6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15524469 15524450 |
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| DOI: | 10.1038/s41589-019-0329-z |