1. in this paper we report synthesis of new substituted benzene sulfonohydrazone by the reaction of aniline with furo [3,4-b] pyridine-5,7- dione to give 2-(phenylcarbamoyl) nicotinic acid (1) which can be convert to 6- phenyl -5H- pyrrolo[3,4-b] pyridine -5,7(6H)- dione (2) by its reaction with acetic anhydride in the presence of sodium acetate. This compound was treated with chlorosulfuric acid to give 4-(5,7- dioxo-5,7- dihydro-6H- pyrrolo [3,4-b] pyridine 6-yl) benzenesulfonyl chloride (3). The compound (3) was reacted with hydrazine hydrate to give hydrazone (4). Lastly, the resulted hydrazone (4) was handled with numbers of aromatic aldehydes and ketones to give substituted benzene sulfonohydrazones (5- 12).