Protection against autoimmunity is driven by thymic epithelial cell–mediated regulation of Tregdevelopment

التفاصيل البيبلوغرافية
العنوان: Protection against autoimmunity is driven by thymic epithelial cell–mediated regulation of Tregdevelopment
المؤلفون: Ari Waisman, Pawel Durek, Nicole Puertas, Mir-Farzin Mashreghi, Marianne R. Spalinger, Stefan Floess, Mirjam Lutz, Ekaterina Friebel, Benedict Becher, Florian Ingelfinger, Florian Mair, Ana Amorim, Claudia Haftmann, Stefanie Schärli, Pascale Zwicky, Burkhard Becher, Jochen Huehn, René Riedel, Jan Kisielow, Brian P. Leung
المصدر: Science Immunology. 6
بيانات النشر: American Association for the Advancement of Science (AAAS), 2021.
سنة النشر: 2021
مصطلحات موضوعية: medicine.anatomical_structure, T cell, Immunology, Thymic epithelial cell, medicine, Cancer research, General Medicine, Biology, medicine.disease_cause, Autoimmunity
الوصف: Medullary thymic epithelial cells (mTECs) are key antigen-presenting cells mediating T cell tolerance to prevent harmful autoimmunity. mTECs both negatively select self-reactive T cells and promote...
تدمد: 2470-9468
DOI: 10.1126/sciimmunol.abf3111
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f35fecd808f2c421a19daed277a4e0a9
https://doi.org/10.1126/sciimmunol.abf3111
رقم الانضمام: edsair.doi...........f35fecd808f2c421a19daed277a4e0a9
قاعدة البيانات: OpenAIRE
الوصف
تدمد:24709468
DOI:10.1126/sciimmunol.abf3111