Peutz-Jeghers syndrome is an inherited, autosomal dominant disorder, characterized by hamartomatous polyps in the gastrointestinal tract and pigmented lesions in mucocutaneous membranes and skin. The polyps can lead to intestinal obstruction due to intussusception. Intussusception may recur in some patients, but synchronous intussusceptions are rare. A 36 years old man was admitted to hospital with abdominal pain. The abdominal tomography revealed an obstruction in the small intestine caused by invagination and a polyp in the large intestine. He had an operation due to intestinal obstruction caused by polyps 16 years ago. The patient was operated. Segmental ileum resections were performed in two different parts of ileum. The colonic polyp was removed by colotomy. The presented case is interesting because of recurrent and synchronous intussusceptions associated with Peutz-Jeghers syndrome. We want to emphasize that follow-up of patients is important as intussusception may recur.