Assessing Process Mass Intensity and Waste via an aza-Baylis–Hillman Reaction
| العنوان: | Assessing Process Mass Intensity and Waste via an aza-Baylis–Hillman Reaction |
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| المؤلفون: | Rodolfo F. Gómez-Biagi, Andrew P. Dicks |
| المصدر: | Journal of Chemical Education. 92:1938-1942 |
| بيانات النشر: | American Chemical Society (ACS), 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Green chemistry, Addition reaction, Allylic rearrangement, Process (engineering), Chemistry, Aza-Baylis–Hillman reaction, Organic chemistry, Context (language use), General Chemistry, Biochemical engineering, E factor, Mass efficiency, Education |
| الوصف: | A synthetic procedure is outlined where upper-level undergraduate organic chemistry students perform a two-week, semimicroscale aza-Baylis–Hillman reaction to generate an allylic sulfonamide product. Students evaluate several green chemistry reaction metrics of industrial importance (process mass intensity (PMI), E factor, and reaction mass efficiency) and specifically learn the pivotal role that PMI plays in improving operational sustainability. Advantages and disadvantages of the various metrics are highlighted within the context of a multicomponent transformation eliciting current research activity. |
| تدمد: | 1938-1328 0021-9584 |
| DOI: | 10.1021/acs.jchemed.5b00249 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ee4932f71da889249cadf1c3454e7178 https://doi.org/10.1021/acs.jchemed.5b00249 |
| رقم الانضمام: | edsair.doi...........ee4932f71da889249cadf1c3454e7178 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19381328 00219584 |
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| DOI: | 10.1021/acs.jchemed.5b00249 |