Summary Objectives: The aim of this study was to investigate the effect of I-gelTM laryngeal mask airway on intraocular pressure (IOP) in children with strabismus undergoing balanced anesthesia with sevoflurane or desflurane. Methods: Forty-seven children, ASA physical status I, were scheduled for elective strabismus surgery. Patients were randomly assigned to one of the two inhalation anesthetic groups. Sevoflurane group comprised of 27 children, and desflurane group comprised of 20 children. Anesthesia was induced and maintained with sevoflurane or desflurane. No muscle relaxant was used. IOPs were measured before anesthesia, at 2 and 5 min after insertion of I-gelTM and after removal of I-gelTM. IOP measurements were obtained by Tonopen®. Results: Intraocular pressure significantly decreased 2 min after insertion of I-gelTM in both sevoflurane and desflurane groups (P