Validation of the 2022 American College of Rheumatology/EULAR classification criteria for Takayasu arteritis
| العنوان: | Validation of the 2022 American College of Rheumatology/EULAR classification criteria for Takayasu arteritis |
|---|---|
| المؤلفون: | Alessandro Tomelleri, Roberto Padoan, Chengappa G Kavadichanda, Augustine Jose, Kritika Singh, Luca Iorio, Upendra Rathore, Emma Rinaldi, Elena Baldissera, Vikas Agarwal, Lorenzo Dagna, Corrado Campochiaro, Durga Prasanna Misra |
| المصدر: | Rheumatology. |
| بيانات النشر: | Oxford University Press (OUP), 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Rheumatology, Pharmacology (medical) |
| الوصف: | Objectives The present study validates the 2022 ACR/European Alliance of Associations for Rheumatology (EULAR) classification criteria for Takayasu’s arteritis (TAK), compared with the 1990 ACR TAK classification criteria. Methods The fulfilment of 2022 ACR/EULAR and 1990 ACR TAK criteria from four referral centres was assessed for TAK compared with extracranial giant cell arteritis (EC-GCA) and other controls. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), likelihood ratio of a positive test (LR+) or negative test (LR–), and area under receiver operating characteristics curve (AUC) were calculated. Results Among 504 patients with TAK (404 females) and 222 controls (151 females, 144 patients with EC-GCA), the 2022 ACR/EULAR criteria had better sensitivity (95.83% vs 82.94%) and NPV, but poorer specificity (63.51% vs 90.54%), PPV, LR+, LR– and AUC at the pre-determined cut-offs than the 1990 ACR criteria. The 2022 ACR/EULAR criteria had greater specificity (76.06% vs 57.62%) and AUC (0.845 vs 0.771), with similar sensitivity (93% vs 96.53%) in males as in females. The 2022 ACR/EULAR criteria performed similarly with only EC-GCA as controls (sensitivity 95.83%, specificity 60.42%, AUC 0.781). Sensitivity remained similar, whereas specificity was higher for 40–60 years vs Conclusion The poor specificity of the 2022 ACR/EULAR TAK criteria in real-life settings was improved by increasing the cut-off to 6 or 7, or removing the point for female sex. |
| تدمد: | 1462-0332 1462-0324 |
| DOI: | 10.1093/rheumatology/kead161 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ebd345d7075bf1e9615a42fd50e05de1 https://doi.org/10.1093/rheumatology/kead161 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........ebd345d7075bf1e9615a42fd50e05de1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14620332 14620324 |
|---|---|
| DOI: | 10.1093/rheumatology/kead161 |