ICF experiments planned for the proposed US National Ignition Facility [NIF] will produce emissions of neutrons, x rays, debris, and shrapnel. The NIF Target Area [TA] must acceptably confine these emissions and respond to their effects to allow an efficient rate of experiments, from 600 to possibly 1500 per year, and minimal down time for maintenance. Detailed computer code predictions of emissions are necessary to study their effects and impacts on Target Area operations. Preliminary results show that the rate of debris shield transmission loss [and subsequent periodicity of change‐out] due to ablated material deposition is acceptable, neutron effects on optics are manageable, and preliminary safety analyses show a facility rating of low hazard, non‐nuclear. Therefore, NIF Target Area design features such as fused silica debris shields, refractory first wall coating, and concrete shielding are effective solutions to confinement of ICF experiment emissions.