A Comparison of the Sex-Specific Incidence of Immune Thrombocytopenia in Children, Teenagers, and Adults in the General Practice Research Database
| العنوان: | A Comparison of the Sex-Specific Incidence of Immune Thrombocytopenia in Children, Teenagers, and Adults in the General Practice Research Database |
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| المؤلفون: | Lin Li, James A. Kaye, Mellissa Yong, W. Marieke Schoonen |
| المصدر: | Blood. 114:3502-3502 |
| بيانات النشر: | American Society of Hematology, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | medicine.medical_specialty, Pediatrics, business.industry, Incidence (epidemiology), Immunology, Cell Biology, Hematology, Biochemistry, Sex specific, Immune thrombocytopenia, Epidemiology, General practice, Medicine, Autoimmune condition, business, Database research, Disease burden |
| الوصف: | Abstract 3502 Poster Board III-439 Background Immune thrombocytopenia (ITP) is an autoimmune condition characterized by low blood platelet counts. It has been reported that the epidemiology of ITP in the pediatric population ( Methods We identified all patients with a first-time diagnosis of ITP recorded in the GPRD during the period from 1990 to 2005. Age- and sex-specific incidences of ITP were estimated as the number of patients with a first-time recorded diagnosis of ITP divided by the person-time contributed by all subjects in the database who did not have a diagnosis of ITP. Results Of the total of 1,146 incident cases of ITP among 29.2 million person-years (PY) of observation from 1990 to 2005, we observed 257 incident cases of pediatric ITP ( Conclusions Our results showed an interaction between age and sex with ITP incidence, suggesting that patterns of disease burden differ among children, teenagers, and the adult population. Further investigation into these differences, including comorbidities and treatment practices is warranted. Financial disclosure This study was supported by Amgen Inc. Disclosures: Yong: Amgen Inc.: Employment, Equity Ownership. Schoonen:Amgen Inc.: Employment, Equity Ownership. Kaye:Amgen Inc.: Research Funding. |
| تدمد: | 1528-0020 0006-4971 |
| DOI: | 10.1182/blood.v114.22.3502.3502 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::e5019be9ed6270a8e2db4beb7189162f https://doi.org/10.1182/blood.v114.22.3502.3502 |
| رقم الانضمام: | edsair.doi...........e5019be9ed6270a8e2db4beb7189162f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15280020 00064971 |
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| DOI: | 10.1182/blood.v114.22.3502.3502 |