EVALUATION OF A MALARIA RAPID DIAGNOSTIC TEST FOR ASSESSING THE BURDEN OF MALARIA DURING PREGNANCY
| العنوان: | EVALUATION OF A MALARIA RAPID DIAGNOSTIC TEST FOR ASSESSING THE BURDEN OF MALARIA DURING PREGNANCY |
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| المؤلفون: | Sodiomon B. Sirima, Robert D. Newman, Mathias Yameogo, Lauren M. Singer, Gail Stennies, Allisyn C. Moran, Romial Sawadogo, Amidou Diarra, John W. Barnwell, Curtis S. Huber, Amadou T. Konaté, Monica E. Parise |
| المصدر: | The American Journal of Tropical Medicine and Hygiene. 70:481-485 |
| بيانات النشر: | American Society of Tropical Medicine and Hygiene, 2004. |
| سنة النشر: | 2004 |
| مصطلحات موضوعية: | Rapid diagnostic test, education.field_of_study, Pregnancy, business.industry, Population, Parasitemia, Dipstick, Gold standard (test), medicine.disease, Infectious Diseases, Virology, parasitic diseases, Immunology, Gestation, Medicine, Parasitology, business, education, Malaria |
| الوصف: | Plasmodium falciparum infection during pregnancy may cause placental malaria and subsequently low birth weight, primarily through the placental sequestration of infected red blood cells. Measuring the burden of malaria during pregnancy usually involves determining the prevalence of placental malaria infection through microscopic ex- amination of placental blood films, a difficult and error-prone process. A number of rapid diagnostic tests (RDTs) for malaria have been developed, most of them immunochromatographic dipstick assays. However, none have been tested for the direct determination of malaria antigen in placental blood. We undertook an evaluation of the Malaria Rapid Test (MAKROmed ®) in determining placental malaria infection. The prevalence of placental parasitemia was 22.6% by microscopy, 51.0% by a polymerase chain reaction (PCR), and 43.1% by RDT. When the PCR was used as the gold standard, RDTs had a sensitivity of 89% and a specificity of 76%. The MAKROmed RDT was highly sensitive in the detection of placental malaria, but had lower than expected specificity. |
| تدمد: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.2004.70.481 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::e48695ccbe266f892689e733a784a5a4 https://doi.org/10.4269/ajtmh.2004.70.481 |
| رقم الانضمام: | edsair.doi...........e48695ccbe266f892689e733a784a5a4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14761645 00029637 |
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| DOI: | 10.4269/ajtmh.2004.70.481 |