Prognostic impact of SYNTAX II score in patients with cardiogenic shock complicating ST-elevation myocardial infarction: analysis of an 10-year all-comers registry
| العنوان: | Prognostic impact of SYNTAX II score in patients with cardiogenic shock complicating ST-elevation myocardial infarction: analysis of an 10-year all-comers registry |
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| المؤلفون: | J.C Sanmartin Pena, P Rigueiro Veloso, R Agra Bermejo, M Fernandez Alvarez, B Cid Alvarez, D Lopez Otero, J R Gonzalez Juanatey, B Alvarez Alvarez, P Tasende Rey, J.M. Garcia Acuna, J Lopez Pais, R. Trillo Nouche, Maria Juskova |
| المصدر: | European Heart Journal. 41 |
| بيانات النشر: | Oxford University Press (OUP), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, Syntax (programming languages), St elevation myocardial infarction, business.industry, Internal medicine, Cardiogenic shock, medicine, Cardiology, In patient, Cardiology and Cardiovascular Medicine, medicine.disease, business |
| الوصف: | Background The SYNTAX II score (SS-II) can predict 4-year outcomes in patients with complex coronary artery disease and ST-segment elevation myocardial infarction (STEMI). Nonetheless, the prognostic value of SS-II for a cardiogenic shock (CS) in the setting of STEMI has not been assessed. Purpose This study aimed to investigate the predictive impact of SS-II in patients with CS complicating STEMI undergoing primary percutaneous coronary intervention, and whether SS-II adds prognostic information to predict major adverse cardiac events (MACE) and all-cause death in this population. Methods This prospective cohort study included 1965 consecutive patients with STEMI who underwent primary-PCI between January 2008 and December 2017. The cohort of patients with CS (n=153) was identified and divided into three groups based on SS-II tertiles [SS-II low tertile Results Amongst the cohort of patients with CS mean age was 68.4±14.0 years, 69.2% were male and 51.6% presented with anterior STEMI (mean SSII was 45.1±14). In-hospital mortality was significantly higher in the high SS-II tertile (85.7% vs. 38.9% vs 24.4%, p≤0.001) compared with SS-II intermediate and low tertiles. During follow-up (median 2.5 years), SS-II was positively correlated with MACE (89.3% (high SS-II) vs. 52.8% (int SS-II) vs. 42.2% (low SS-II), p≤0.001), and with all-cause mortality (89.3% vs 44.4% vs 26.7%, p≤0.001). The SS-II was also an independent predictor of MACE (HR=1.042, 95% CI: 1.020–1.063, p=0.000) and all-cause mortality during follow-up (HR=1.056, 95% CI: 1.033–1.079, p=0.000) Conclusion In a real-world cohort of patients with STEMI related CS, the SS-II added important prognostic information, being an independent predictor of MACE and all-cause mortality during follow-up. Image 1 Funding Acknowledgement Type of funding source: None |
| تدمد: | 1522-9645 0195-668X |
| DOI: | 10.1093/ehjci/ehaa946.1789 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::e469f3c30303e268cf715969b8b3bf94 https://doi.org/10.1093/ehjci/ehaa946.1789 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........e469f3c30303e268cf715969b8b3bf94 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
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| DOI: | 10.1093/ehjci/ehaa946.1789 |