Patent foramen ovale—When to close and how?
| العنوان: | Patent foramen ovale—When to close and how? |
|---|---|
| المؤلفون: | Sven Möbius-Winkler, Albrecht Günther, P. Christian Schulze, Marcus Franz, Carsten M. Klingner, Aurel Maloku, Ali Hamadanchi, Gudrun Dannberg |
| المصدر: | Herz. 46:445-451 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, medicine.disease, Surgery, medicine.anatomical_structure, Pfo closure, Migraine, Occlusion, medicine, Patent foramen ovale, Number needed to treat, Platelet aggregation inhibitor, Cardiology and Cardiovascular Medicine, business, Stroke, Foramen ovale (heart) |
| الوصف: | Closure of a patent foramen ovale (PFO) in patients after cryptogenic/cardioembolic stroke is recommended by current guidelines for patients who are 16–60 years of age with a high-risk PFO (class of recommendation A, level of evidence I). The use of double-disk occlusion devices followed by antiplatelet therapy is recommended. The procedure of interventional PFO closure compared with other interventions in cardiology is rather easy to learn. However, it should be performed carefully to avoid postinterventional complications. The number needed to treat (NNT) to avoid one stroke in 5 years in the RESPECT trial was 42, in the CLOSE trial even lower with 20. In the REDUCE trial, the NNT was 28 at 2 years. This can be reduced by longer follow-up, e.g., at 10 years the NNT is 18. While other conditions such as migraine are currently under investigation with respect to the impact of PFO closure, sufficiently powered trials are lacking so that closure in diseases other than stroke should always be individualized. |
| تدمد: | 1615-6692 0340-9937 |
| DOI: | 10.1007/s00059-021-05061-y |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::e3e3ef15106a8fd2288c8805d4d156b4 https://doi.org/10.1007/s00059-021-05061-y |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........e3e3ef15106a8fd2288c8805d4d156b4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16156692 03409937 |
|---|---|
| DOI: | 10.1007/s00059-021-05061-y |