The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic
| العنوان: | The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic |
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| المؤلفون: | Clive S. Mason, Tim Avis, Chenlin Hu, Nabeetha Nagalingam, Manikhandan Mudaliar, Chris Coward, Khurshida Begum, Kathleen Gajewski, M. Jahangir Alam, Eugenie Bassères, Stephen Moss, Stefanie Reich, Esther Duperchy, Keith R. Fox, Kevin W. Garey, David J. Powell |
| المصدر: | Antimicrobial Agents and Chemotherapy. 67 |
| بيانات النشر: | American Society for Microbiology, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Pharmacology, Infectious Diseases, Pharmacology (medical) |
| الوصف: | Clostridioides difficile infection (CDI) causes substantial morbidity and mortality worldwide with limited antibiotic treatment options. Ridinilazole is a precision bisbenzimidazole antibiotic being developed to treat CDI and reduce unacceptably high rates of infection recurrence in patients. |
| تدمد: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.01563-22 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::e3dfee585d13ff4baa8dae74b676bca2 https://doi.org/10.1128/aac.01563-22 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........e3dfee585d13ff4baa8dae74b676bca2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10986596 00664804 |
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| DOI: | 10.1128/aac.01563-22 |