In-hospital glycemic variability and all-cause mortality in patients hospitalized with acute heart failure: analysis of the KorAHF registry
| العنوان: | In-hospital glycemic variability and all-cause mortality in patients hospitalized with acute heart failure: analysis of the KorAHF registry |
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| المؤلفون: | K H Chun, J Oh, C J Lee, S M Kang |
| المصدر: | European Heart Journal. 43 |
| بيانات النشر: | Oxford University Press (OUP), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Cardiology and Cardiovascular Medicine |
| الوصف: | Introduction Glycemic variability (GV) is known to be a poor prognostic marker in various diseases including cardiovascular disease. Purpose We investigated the association of GV with all-cause mortality in patients with acute heart failure (HF). Methods The Korean Acute Heart Failure registry enrolled patients hospitalized for acute HF from 2011 to 2014. Among survivors of the index hospitalization, we analyzed those who had ≥3 blood glucose measurements before discharge. Patients were divided into two groups based on their coefficient of variation (%CV) as an indicator of GV. We investigated all-cause mortality at 6 month and 1 year after discharge. Results The study analyzed 2,617 patients (median age 72 years, 53% male). During the median follow-up period of 11 months, 583 (22%) patients died. Compared to alive patients, patients who died had a significantly higher diabetes prevalence (46% vs. 41%, P=0.035) and higher %CV (31.0% vs. 27.5%, P21%) was associated with lower cumulative survival to all-cause death compared with a low GV (%CV ≤21%) (log-rank P Conclusion A high GV (%CV >21%) before discharge was associated with all-cause mortality within 1 year, especially in non-diabetic acute HF patients. Funding Acknowledgement Type of funding sources: None. |
| تدمد: | 1522-9645 0195-668X |
| DOI: | 10.1093/eurheartj/ehac544.1075 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::dfe96471c60a59ac190e325c290467d0 https://doi.org/10.1093/eurheartj/ehac544.1075 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........dfe96471c60a59ac190e325c290467d0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
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| DOI: | 10.1093/eurheartj/ehac544.1075 |