A case of Helicobacter pylori-negative gastric cancer associated with Cronkhite–Canada Syndrome
| العنوان: | A case of Helicobacter pylori-negative gastric cancer associated with Cronkhite–Canada Syndrome |
|---|---|
| المؤلفون: | Mayumi Yamaguchi, Masaya Tamano, Ryosaku Shirahasi, Yasumi Katayama, Yoshinori Gyotoku, Ikuhiro Kobori, Yuto Suzuki, Shinich Ban, Yo Fujimoto, Kei Funada, Yumi Kusano |
| المصدر: | Clinical Journal of Gastroenterology. 14:123-128 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, biology, business.industry, fungi, Gastroenterology, Cancer, General Medicine, Hepatology, Helicobacter pylori, medicine.disease, biology.organism_classification, 03 medical and health sciences, Foveolar cell, 0302 clinical medicine, Surgical oncology, 030220 oncology & carcinogenesis, Internal medicine, medicine, Adenocarcinoma, 030211 gastroenterology & hepatology, Cronkhite–Canada syndrome, Helicobacter, business |
| الوصف: | A 43-year-old Japanese man diagnosed with Cronkhite-Canada Syndrome (CCS) underwent endoscopic submucosal dissection for Helicobacter pylori-negative gastric cancer. Histologically, the completely resected specimen showed large and small irregular glands composed of foveolar epithelial-like atypical cells, and it was immunohistochemically MUC5AC positive overall, MUC6 positive except for the surface layer and nearby parts, and MUC2 negative. The patient was diagnosed with gastric-phenotype, low-grade, well-differentiated adenocarcinoma. This is a case of gastric cancer developing in CCS definitively without H. pylori infection. We conclude that H. pylori infection is not an absolute condition in gastric cancer associated with CCS. Elucidation of the true malignant potential of CCS excluding the effects of H. pylori infection is needed. |
| تدمد: | 1865-7265 1865-7257 |
| DOI: | 10.1007/s12328-020-01268-4 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::de39fb7bbf41f381bb9f28a18105a564 https://doi.org/10.1007/s12328-020-01268-4 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........de39fb7bbf41f381bb9f28a18105a564 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18657265 18657257 |
|---|---|
| DOI: | 10.1007/s12328-020-01268-4 |