أعرض في EDS

Gender differences in clinical characteristics in wild-type transthyretin amyloidosis cardiomyopathy

التفاصيل البيبلوغرافية
العنوان: Gender differences in clinical characteristics in wild-type transthyretin amyloidosis cardiomyopathy
المؤلفون: S Takashio, M Morioka, M Nishi, N Nakashima, T Yamada, K Hirakawa, S Hanatani, H Usuku, E Yamamoto, K Matsushita, K Kaikita, K Tsujita
المصدر: European Heart Journal. 42
بيانات النشر: Oxford University Press (OUP), 2021.
سنة النشر: 2021
مصطلحات موضوعية: Cardiology and Cardiovascular Medicine
الوصف: Aims A significant male predominance has been reported in wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM). In other words, the female ATTRwt-CM may be overlooked and gender differences in ATTRwt-CM remain unclear. This study aims to examine gender differences in clinical characteristics and diagnostic approaches in ATTRwt-CM. Methods and results We retrospectively evaluated 171 consecutive ATTRwt-CM patients diagnosed at our university hospital between December 2002 and December 2020. Twenty-two patients (12%) were women. Women were significantly older at diagnosis (77.3 years vs. 83.3 years; P Conclusion Women with ATTRwt-CM were predominantly octogenarians, less hypertrophic, and had weaker cardiac uptake of the 99mTc-PYP tracer than men with ATTRwt-CM. These characteristics contribute to the underdiagnosis of ATTRwt-CM in women. The diagnosis of ATTRwt-CM in women is challenging. Therefore, we must be familiar with the clinical characteristics of women with ATTRwt-CM. Funding Acknowledgement Type of funding sources: None.
تدمد: 1522-9645
0195-668X
DOI: 10.1093/eurheartj/ehab724.1812
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dc0c5938856b7eb85e789912c9083f77
https://doi.org/10.1093/eurheartj/ehab724.1812
Rights: OPEN
رقم الانضمام: edsair.doi...........dc0c5938856b7eb85e789912c9083f77
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15229645
0195668X
DOI:10.1093/eurheartj/ehab724.1812