Multiple coronary aneurysms and acute myocardial infarction in a female patient with rhupus: case report and literature review
| العنوان: | Multiple coronary aneurysms and acute myocardial infarction in a female patient with rhupus: case report and literature review |
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| المؤلفون: | F. Zuccarino, Irene Carrión-Barberà, F. A. Escalante, Tarek Carlos Salman-Monte |
| المصدر: | Clinical Rheumatology. 40:1175-1184 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 030203 arthritis & rheumatology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, General Medicine, medicine.disease, Rheumatology, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Internal medicine, Rheumatoid arthritis, Biopsy, Etiology, Cardiology, Medicine, cardiovascular diseases, 030212 general & internal medicine, Myocardial infarction, business, Vasculitis, Artery |
| الوصف: | Coronary artery aneurysms (CAA) are an infrequent cause of coronary artery disease in both systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), most occurring as a result of acute coronary syndromes (ACS). Until now, no cases of CAA have been described in a patient with rhupus syndrome (RhS). Differentiating whether CAA stem from primary vasculitis, atherosclerosis, or a combination of both continues to pose a significant challenge. We present the first described clinical case of a 43-year-old patient with RhS and multiple CAA identified by the presentation of an acute myocardial infarction. The presence of multiple cardiovascular risk factors and the absence of inflammatory findings, both in PET-CT and arterial biopsy, favored an atherosclerotic versus a vasculitic etiology of the CAA. At the time of the aneurysms diagnosis, the patient showed no signs of SLE activity and only moderate RA activity, which underscores the importance of screening for silent coronary aneurysms in these patients, even in subjects exhibiting little apparent activity from their underlying disease. This case also exemplifies the severe impact of atherosclerotic burdens on such patients, demanding vigilance and aggressiveness in its prevention, early diagnosis, and treatment. We hypothesize that RhS could engender an even greater risk of presenting CAA than either SLE or RA on their own, which therefore warrants more careful follow-up in these patients. |
| تدمد: | 1434-9949 0770-3198 |
| DOI: | 10.1007/s10067-020-05313-y |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::da2e603e136f182258421f46ff8c53ce https://doi.org/10.1007/s10067-020-05313-y |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........da2e603e136f182258421f46ff8c53ce |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14349949 07703198 |
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| DOI: | 10.1007/s10067-020-05313-y |