The drive system provides power for high-speed motorized spindle which performance has a direct impact on the machining accuracy of numerical control (NC) machine tools. The motorized spindle drive system has a great influence on high precision computer numerical control (CNC) machine tools. This paper proposed a current hysteresis control design method based on the semi-physical simulation model for a motorized spindle driven system. The control system built-in Simulink could be packed and download to a digital signal processing (DSP) chip to verify the performance, which will save testing time and reduce development costs. A verification case was presented, and the results showed that the proposed semi-physical model was effective and could be used to accelerate the development of a driven system for motorized spindle.