Phospholipid-modified carbon fiber brush electrode for the detection of dopamine and 3,4-dihydroxyphenylacetic acid
| العنوان: | Phospholipid-modified carbon fiber brush electrode for the detection of dopamine and 3,4-dihydroxyphenylacetic acid |
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| المؤلفون: | Petr Barták, Jan Rozsypal, Hana Tomková, Jana Štěpánková, Veronika Müllerová, Jana Skopalová, Radek Jerga |
| المصدر: | Monatshefte für Chemie - Chemical Monthly. 150:395-400 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 010405 organic chemistry, Inorganic chemistry, Phospholipid, General Chemistry, 010402 general chemistry, Phosphate, 01 natural sciences, 0104 chemical sciences, Dielectric spectroscopy, Hexane, chemistry.chemical_compound, chemistry, Electrode, Moiety, Cyclic voltammetry, Voltammetry |
| الوصف: | Different procedures for modification of carbon fiber brush electrode (CFBE) with phospholipids were investigated using cyclic voltammetry and electrochemical impedance spectroscopy. Simple immersion of the preanodized electrode into hexane solution of asolectin (a mixture of soybean phospholipids) followed by formation of the phospholipid layer in NaCl solution was the most effective procedure. Phospholipid layer-modified electrode (PL-CFBE) was applied to detect dopamine and its metabolite, 3,4 dihydroxyphenylacetic acid, using differential pulse and square-wave voltammetry in phosphate buffer solution of pH 6.5. Accumulation of dopamine, supported by electrostatic interactions between positively charged amino group and negatively charged phosphate moiety of the layer, enhanced sensitivity of PL-CFBE compared to bare CFBE. On the contrary, repulsive interaction between 3,4 dihydroxyphenylacetate anion and negatively charged phosphate moiety of the layer suppressed PL-CFBE sensitivity, measured as a slope of calibration dependence. |
| تدمد: | 1434-4475 0026-9247 |
| DOI: | 10.1007/s00706-019-2371-7 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ce812e94466db0403fc20f3f83519baf https://doi.org/10.1007/s00706-019-2371-7 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........ce812e94466db0403fc20f3f83519baf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14344475 00269247 |
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| DOI: | 10.1007/s00706-019-2371-7 |