Current Views on the Interval Between Neoadjuvant Chemoradiation and Surgery for Rectal Cancer
| العنوان: | Current Views on the Interval Between Neoadjuvant Chemoradiation and Surgery for Rectal Cancer |
|---|---|
| المؤلفون: | Bruno Augusto Alves-Martins, Maria Emilia Carvalho e Carvalho, Luiz Felipe de Campos-Lobato |
| المصدر: | Current Colorectal Cancer Reports. 13:234-239 |
| بيانات النشر: | Springer Science and Business Media LLC, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, Hepatology, business.industry, Colorectal cancer, Standard treatment, Gastroenterology, Stage ii, medicine.disease, Colorectal surgery, Surgery, Sphincter preservation, 03 medical and health sciences, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Overall survival, Medicine, 030211 gastroenterology & hepatology, Rectal resection, business, Complete response |
| الوصف: | Neoadjuvant chemoradiation (CRT) has been established as standard treatment for stage II and III rectal cancer, and delayed interval between CRT and rectal resection has emerged as appropriate treatment due to the marked benefits associated with this approach. Despite favorable findings on downstaging and pathological complete response without increasing in morbidity and mortality, no significant improvement in sphincter preservation rate and rectal cancer overall survival has been observed with the current recommended 6–8-week interval. Trials are currently underway and may provide answers regarding the optimal interval between CRT and surgical resection, but until now, the best interval between CRT and surgery remains unclear. |
| تدمد: | 1556-3804 1556-3790 |
| DOI: | 10.1007/s11888-017-0370-9 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::c91f72d5ec81dcd63e34ef399cb12055 https://doi.org/10.1007/s11888-017-0370-9 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........c91f72d5ec81dcd63e34ef399cb12055 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15563804 15563790 |
|---|---|
| DOI: | 10.1007/s11888-017-0370-9 |