Outcomes of truncal valve replacement in neonates and infants: a meta-analysis
| العنوان: | Outcomes of truncal valve replacement in neonates and infants: a meta-analysis |
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| المؤلفون: | William A. Hardy, Lillian Kang, Joseph W. Turek, T. Konrad Rajab |
| المصدر: | Cardiology in the Young. 33:673-680 |
| بيانات النشر: | Cambridge University Press (CUP), 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Pediatrics, Perinatology and Child Health, General Medicine, Cardiology and Cardiovascular Medicine |
| الوصف: | Background:Infants with truncus arteriosus typically undergo repair by repurposing the truncal valve as the neo-aortic valve and using a valved conduit homograft for the neo-pulmonary valve. In cases where the native truncal valve is too insufficient for repair, it is replaced, but this is a rare occurrence with a paucity of data, especially in the infant population. Here, we conduct a meta-analysis to better understand the outcomes of infant truncal valve replacement during the primary repair of truncus arteriosus.Methods:We systematically reviewed PubMed, Scopus, and CINAHL for all studies reporting infant (Results:Sixteen studies with 41 infants who underwent truncal valve replacement were included. The truncal valve replacement types were homografts (68.8%), mechanical valves (28.1%), and bioprosthetic valves (3.1%). Overall early mortality was 49.4% (95% CI: 28.4–70.5). The pooled late mortality rate was 15.3%/year (95% CI: 5.8–40.7). The overall rate of truncal valve reintervention was 21.7%/year (95% CI: 8.4–55.7).Conclusions:Infant truncal valve replacement has poor early and late mortality as well as high rates of reintervention. Truncal valve replacement therefore remains an unsolved problem in congenital cardiac surgery. Innovations in congenital cardiac surgery, such as partial heart transplantation, are required to address this. |
| تدمد: | 1467-1107 1047-9511 |
| DOI: | 10.1017/s1047951123000604 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::c7b143bebc45e3d8fcf16f362457db19 https://doi.org/10.1017/s1047951123000604 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........c7b143bebc45e3d8fcf16f362457db19 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14671107 10479511 |
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| DOI: | 10.1017/s1047951123000604 |