Successful Abdominal Organ Donation after Brain Death in a Patient with a Biventricular Assist Device: Extending Extended Criteria
العنوان: | Successful Abdominal Organ Donation after Brain Death in a Patient with a Biventricular Assist Device: Extending Extended Criteria |
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المؤلفون: | Louis A. Lanza, K. Sudhakar Reddy, David C. Mulligan, D. Eric Steidley, Susanne G. Carpenter, Adyr A. Moss, David D. Douglas |
المصدر: | Open Journal of Organ Transplant Surgery. :32-35 |
بيانات النشر: | Scientific Research Publishing, Inc., 2013. |
سنة النشر: | 2013 |
مصطلحات موضوعية: | medicine.medical_specialty, education.field_of_study, business.industry, Polycystic liver disease, Cardiogenic shock, medicine.medical_treatment, Population, medicine.disease, Surgery, Transplantation, Blood chemistry, Internal medicine, Ventricular assist device, medicine, Cardiology, Myocardial infarction, Organ donation, education, business |
الوصف: | Few studies address the potential for donation after brain death (DBD) in the limited population of patients with ongoing mechanical circulatory support (MCS). A case study was conducted reviewing available records of both donor and recipient, and available literature. The donor was a young female with an acute myocardial infarction precipitating emergent off-pump 2-vessel bypass graft complicated by profound cardiogenic shock refractory to inotropes and intra-aortic balloon pump. A heparin drip was started following percutaneous placement of a left ventricular-assist device (TandemHeart?) which improved her hemodynamics to stabilize for transfer. She ultimately required surgical placement of biventricular assist device (CentraMag?) to normalize hemodynamics. Two days post-operatively, she developed a cerebellar hemorrhage and was declared brain dead. Pre-donation blood chemistry showed adequate end-organ function. Both kidneys were placed locally. The liver was rejected for two regional status 1 patients and by all other local centers. We accepted the liver for a patient with polycystic liver disease with a MELD exception score of 20. The recipient is now 4 years post-transplant with excellent graft function. Extending donor criteria to include MCS patients can result in successful transplantation and should be considered in selected circumstances once satisfactory donor end-organ function is established. |
تدمد: | 2163-9493 2163-9485 |
DOI: | 10.4236/ojots.2013.32006 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::c55a132ca6a7995f491e738faaf53090 https://doi.org/10.4236/ojots.2013.32006 |
Rights: | OPEN |
رقم الانضمام: | edsair.doi...........c55a132ca6a7995f491e738faaf53090 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 21639493 21639485 |
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DOI: | 10.4236/ojots.2013.32006 |