Is the Recent Rise in Type 2 Diabetes Incidence From 1984 to 2007 Explained by the Trend in Increasing BMI?
| العنوان: | Is the Recent Rise in Type 2 Diabetes Incidence From 1984 to 2007 Explained by the Trend in Increasing BMI? |
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| المؤلفون: | Peter H. Whincup, Mary C Thomas, Richard W Morris, S. Goya Wannamethee, Lucy T. Lennon, Sarah Hardoon |
| المصدر: | Diabetes Care. 33:1494-1496 |
| بيانات النشر: | American Diabetes Association, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Advanced and Specialized Nursing, Gerontology, business.industry, Endocrinology, Diabetes and Metabolism, Incidence (epidemiology), Hazard ratio, Type 2 diabetes, Overweight, medicine.disease, Obesity, Cohort, Internal Medicine, Medicine, medicine.symptom, business, Body mass index, Demography, Cohort study |
| الوصف: | OBJECTIVE To estimate the extent to which increasing BMI may explain the rise in type 2 diabetes incidence in British men from 1984 to 2007. RESEARCH DESIGN AND METHODS A representative cohort ratio of 6,460 British men was followed-up for type 2 diabetes incidence between 1984 (aged 45–65 years) and 2007 (aged 67–89 years). BMI was ascertained at regular intervals before and during the follow-up. RESULTS Between 1984–1992 and 1999–2007, the age-adjusted hazard of type 2 diabetes more than doubled (hazard ratio 2.33 [95% CI 1.75–3.10]). Mean BMI rose by 1.42 kg/m2 (95% CI 1.10–1.74) between 1984 and 1999; this could explain 26% (95% CI 17–38) of the type 2 diabetes increase. CONCLUSIONS An appreciable portion of the rise in type 2 diabetes can be attributed to BMI changes. A substantial portion remains unexplained, possibly associated with other determinants such as physical activity. This merits further research. |
| تدمد: | 1935-5548 0149-5992 |
| DOI: | 10.2337/dc09-2295 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::c116999708c3ab0e55fa900faa201ad8 https://doi.org/10.2337/dc09-2295 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........c116999708c3ab0e55fa900faa201ad8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19355548 01495992 |
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| DOI: | 10.2337/dc09-2295 |