A single site mutation significantly improves the thermostability and activity of heparinase I from Bacteroides eggerthii
| العنوان: | A single site mutation significantly improves the thermostability and activity of heparinase I from Bacteroides eggerthii |
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| المؤلفون: | Hua-Ping Zhou, Chen-Yuan Zhu, Jian Gao, Ye-Wang Zhang, Wen-Bin Su |
| المصدر: | Biocatalysis and Biotransformation. 40:226-232 |
| بيانات النشر: | Informa UK Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Mutation, FoldX, Biochemistry, Chemistry, Single site, Bacteroides eggerthii, medicine, Heparinase I, medicine.disease_cause, Catalysis, Biotechnology, Thermostability |
| الوصف: | The applications of heparinase I in the preparation of low molecular weight heparin were limited due to the poor thermostability. In this work, the Foldx was used to calculate the folding free ener... |
| تدمد: | 1029-2446 1024-2422 |
| DOI: | 10.1080/10242422.2021.1976757 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::b6beb601751fdd6ab33d421c6f0f4a21 https://doi.org/10.1080/10242422.2021.1976757 |
| رقم الانضمام: | edsair.doi...........b6beb601751fdd6ab33d421c6f0f4a21 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10292446 10242422 |
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| DOI: | 10.1080/10242422.2021.1976757 |