Effectiveness of the Nanosilver/TiO2-Chitosan Antiviral Filter on the Removal of Viral Aerosols
| العنوان: | Effectiveness of the Nanosilver/TiO2-Chitosan Antiviral Filter on the Removal of Viral Aerosols |
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| المؤلفون: | Wan-Tien Shen, Chien Su, I-Jen Wang, Chun-Hsuan Bai, Ming-Hsuan Tsai, Kuo-Pin Yu, Yen Chi Chen |
| المصدر: | Journal of Aerosol Medicine and Pulmonary Drug Delivery. 34:293-302 |
| بيانات النشر: | Mary Ann Liebert Inc, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Chromatography, Scanning electron microscope, viruses, technology, industry, and agriculture, Pharmaceutical Science, Airborne transmission, law.invention, Aerosol, Chitosan, chemistry.chemical_compound, chemistry, Filter (video), law, Pharmacology (medical), Particle counter, Filtration, Air filter |
| الوصف: | Background: The precaution of airborne transmission of viruses, such as influenza, SARS, MERS, and COVID-19, is essential for reducing infection. In this study, we applied a zero-valent nanosilver/titania-chitosan (nano-Ag0/TiO2-CS) filter bed, whose broad-spectrum antimicrobial efficacy has been proven previously, for the removal of viral aerosols to minimize the risk of airborne transmission. Methods: The photochemical deposition method was used to synthesize the nano-Ag0/TiO2-CS antiviral material. The surface morphology, elemental composition, and microstructure of the nano-Ag0/TiO2-CS were analyzed by a scanning electron microscopy/energy dispersive X-ray spectroscopy and a transmission electron microscopy, respectively. The MS2 bacteriophages were used as surrogate viral aerosols. The antiviral efficacy of nano-Ag0/TiO2-CS was evaluated by the MS2 plaque reduction assay (PRA) and filtration experiments. In the filtration experiments, the MS2 aerosols passed through the nano-Ag0/TiO2-CS filter, and the MS2 aerosol removal efficiency was evaluated by an optical particle counter and culture method. Results and Conclusions: In the MS2 PRA, 3 g of nano-Ag0/TiO2-CS inactivated 97% of MS2 bacteriophages in 20 mL liquid culture (2 ± 0.5 × 1016 PFU/mL) within 2 hours. The removal efficiency of nano-Ag0/TiO2-CS filter (thickness: 6 cm) for MS2 aerosols reached up to 93%. Over 95% of MS2 bacteriophages on the surface of the nano-Ag0/TiO2-CS filter were inactivated within 20 minutes. The Wells-Riley model predicted that when the nano-Ag0/TiO2-CS filter was used in the ventilation system, airborne infection probability would reduce from 99% to 34.6%. The nano-Ag0/TiO2-CS filter could remain at 50% of its original antiviral efficiency after continuous operation for 1 week, indicating its feasibility for the control of the airborne transmission. |
| تدمد: | 1941-2703 1941-2711 |
| DOI: | 10.1089/jamp.2020.1607 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::b3dff11f62c610b5afb01de5b96c57c7 https://doi.org/10.1089/jamp.2020.1607 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........b3dff11f62c610b5afb01de5b96c57c7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19412703 19412711 |
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| DOI: | 10.1089/jamp.2020.1607 |