Superacid Catalyzed Hydroxyalkylation of Aromatics with Ethyl Trifluoropyruvate: A New Synthetic Route to Mosher’s Acid Analogs
| العنوان: | Superacid Catalyzed Hydroxyalkylation of Aromatics with Ethyl Trifluoropyruvate: A New Synthetic Route to Mosher’s Acid Analogs |
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| المؤلفون: | Ping Yan, G. K. Surya Prakash, George A. Olah, Béla Török |
| المصدر: | Synlett. :0527-0531 |
| بيانات النشر: | Georg Thieme Verlag KG, 2003. |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | chemistry.chemical_compound, Ethyl trifluoropyruvate, chemistry, Phenyl acetic acid, Organic Chemistry, chemistry.chemical_element, Organic chemistry, Superacid, Ethyl ester, Gallium, Mosher's acid, Trifluoromethanesulfonate, Catalysis |
| الوصف: | A new superacid catalyzed Friedel-Crafts hydroxyalkylation of aromatics with ethyl trifluoropyruvate is described. The trifluoromethanesulfonic acid or gallium(III) trifluoromethanesulfonate catalyzed reactions give α-hydroxy α-trifluoromethyl phenyl acetic acid ethyl ester and its derivatives (analogs of Mosher's acid) in good yields for both highly activated hetero-aromatics and substituted benzenes. |
| تدمد: | 1437-2096 0936-5214 |
| DOI: | 10.1055/s-2003-37517 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::b3df426ad3b614ddf61a04ba3667249a https://doi.org/10.1055/s-2003-37517 |
| رقم الانضمام: | edsair.doi...........b3df426ad3b614ddf61a04ba3667249a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14372096 09365214 |
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| DOI: | 10.1055/s-2003-37517 |