Enhancement of the cytotoxicities and antioxidative activities of white ginseng extract by hydrolysis under mild acidic conditions
| العنوان: | Enhancement of the cytotoxicities and antioxidative activities of white ginseng extract by hydrolysis under mild acidic conditions |
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| المؤلفون: | Joo-Yeon Lee, Kee-Tae Kim, Hee-Sook Jee, Kyung Hoon Chang, Hyun-Dong Paik, Se-Ho Park |
| المصدر: | Food Science and Biotechnology. 23:173-178 |
| بيانات النشر: | Springer Science and Business Media LLC, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Antioxidant, DPPH, medicine.medical_treatment, Applied Microbiology and Biotechnology, Hydrolysate, chemistry.chemical_compound, Hydrolysis, chemistry, Biochemistry, Ginsenoside, medicine, MTT assay, Food science, Citric acid, Cytotoxicity, Food Science, Biotechnology |
| الوصف: | White ginseng extract (WGE) was hydrolyzed with organic acids to increase the yield of ginsenoside Rg3 which has high bio-functional activities. The condition of hydrolysis by citric acid was studied to maximize a production of ginsenoside Rg3. The total content of ginsenoside Rg3 in WGE treated with 10% citric acid at 110°C for 1 h was 10-folds greater than that of commercial extract. The antitumor and antioxidant activities of WGE and the acid-hydrolysates were evaluated via an MTT assay and the DPPH method, respectively. At 1.0 mg/mL, hydrolysates inhibited the proliferation of AGS and Hep-2 cells by more than 90%, but did not inhibit their growth. It suggests that citric acid hydrolysis enhances the content of Rg3. In addition, the acid hydrolysates evidenced a free radical scavenging activity of 80% at a concentration of 4.0 mg/mL, while WGE exhibited only a 49% free radical scavenging activity at the same concentration. |
| تدمد: | 2092-6456 1226-7708 |
| DOI: | 10.1007/s10068-014-0023-6 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::b2bddc24ac80ebf0b396cade90ba177d https://doi.org/10.1007/s10068-014-0023-6 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........b2bddc24ac80ebf0b396cade90ba177d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20926456 12267708 |
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| DOI: | 10.1007/s10068-014-0023-6 |