التفاصيل البيبلوغرافية
العنوان:
Structure-Activity Relationships Among a New Class of Antiviral Heterosubstituted 2',3'-Dideoxynucleoside Analogues
المؤلفون:
John Gillard , Claire Ashman , Horacio Salomon , Elizabeth Hooker , Haolun Jin , Antonietta R. Belmonte , Nick Cammack , Colleen A. Evans , Wei Wang , Mark A. Wainberg , Bernard Belleau , Dilip M. Dixit , Tarek S. Mansour , H. L. Allan Tse
المصدر:
Nucleosides, Nucleotides and Nucleic Acids . 14:627-635
بيانات النشر:
Informa UK Limited, 1995.
سنة النشر:
1995
مصطلحات موضوعية:
Chemistry , Cell culture , Stereochemistry , 2'3' dideoxynucleoside , Genetics , virus diseases , Molecular Medicine , General Medicine , Biochemistry , Nucleoside , In vitro
الوصف:
3′-Oxa-4′-thiocytidine nucleoside analogues 14–17 were prepared from oxathiolanes 10 and 11, and evaluated for activity against HIV-1 and HBV in vitro. The nucleoside analogues were found to possess potent activities against HIV-1 in a panel of cell lines. Compound 16 is moderately active against HBV in 2.2.15 cells.
تدمد:
1525-7770
DOI:
10.1080/15257779508012439
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2ba7d2627716e74f77ad3cbc8db6125 https://doi.org/10.1080/15257779508012439
رقم الانضمام:
edsair.doi...........b2ba7d2627716e74f77ad3cbc8db6125
قاعدة البيانات:
OpenAIRE