What is the risk of sham surgery in Parkinson disease clinical trials? A review of published reports
| العنوان: | What is the risk of sham surgery in Parkinson disease clinical trials? A review of published reports |
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| المؤلفون: | W. Landau, S. A. Frank, K. Kieburtz, R. Holloway, S. Y.H. Kim |
| المصدر: | Neurology. 66:1788-1789 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Sham surgery, Disease, Placebo, medicine.disease, Surgery, Central nervous system disease, Clinical trial, Internal medicine, Medicine, Neurology (clinical), Risk factor, business, Risk assessment, Adverse effect |
| الوصف: | Placebo, or sham surgery, as a control condition in surgical clinical trials in Parkinson disease (PD) remains controversial. The authors reviewed the adverse effects reported in double blind, placebo surgery controlled trials for PD. Placebo surgeries were generally safe and well tolerated but the number of subjects receiving the procedure was small. Harm occurred more frequently in subjects randomized to the experimental intervention. |
| تدمد: | 1526-632X 0028-3878 |
| DOI: | 10.1212/01.wnl.0000230564.67320.b1 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ab21a00f4c4c1779e2643827922b8e4e https://doi.org/10.1212/01.wnl.0000230564.67320.b1 |
| رقم الانضمام: | edsair.doi...........ab21a00f4c4c1779e2643827922b8e4e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1526632X 00283878 |
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| DOI: | 10.1212/01.wnl.0000230564.67320.b1 |