Does Early Cerebral Near-Infrared Spectroscopy Monitoring Predict Outcome in Neonates with Hypoxic Ischaemic Encephalopathy? A Systematic Review of Diagnostic Test Accuracy
| العنوان: | Does Early Cerebral Near-Infrared Spectroscopy Monitoring Predict Outcome in Neonates with Hypoxic Ischaemic Encephalopathy? A Systematic Review of Diagnostic Test Accuracy |
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| المؤلفون: | Eugene M. Dempsey, Aisling A. Garvey, Geraldine B. Boylan, Andreea M Pavel, Deirdre M. Murray |
| المصدر: | Neonatology. 119:1-9 |
| بيانات النشر: | S. Karger AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pediatrics, medicine.medical_specialty, Neonatal encephalopathy, business.industry, Encephalopathy, Diagnostic test, Cochrane Library, medicine.disease, Hypoxic ischaemic encephalopathy, Objective assessment, Pediatrics, Perinatology and Child Health, medicine, Gestation, Cerebral perfusion pressure, business, Developmental Biology |
| الوصف: | Introduction: Hypoxic ischaemic encephalopathy (HIE) remains one of the top 10 contributors to the global burden of disease. Early objective biomarkers are required. Near-infrared spectroscopy (NIRS) may provide a valuable insight into cerebral perfusion and metabolism. We aimed to determine whether early NIRS monitoring (Methods: We searched PubMed, Scopus, Web of Science, Embase, and The Cochrane Library databases (July 2019). Studies of infants born ≥36+0 weeks gestation with HIE who had NIRS recording commenced before 6 h of life were included. We planned to provide a narrative of all the studies included, and if similar clinically and methodologically, the results would be pooled in a meta-analysis to determine test accuracy. Results: Seven studies were included with a combined total of 161 infants. Only 1 study included infants with mild HIE. A range of different oximeters and probes were utilized with varying outcome measures making comparison difficult. Although some studies showed a trend towards higher cSO2 values before 6 h in infants with adverse neurodevelopmental outcomes, in the majority, this was not significant until beyond 24 h of life. Conclusion: Very little data currently exists to assess the use of early NIRS to predict outcome in infants with HIE. Further studies using a standardized approach are required before NIRS can be evaluated as a potential objective assessment tool for early identification of at-risk infants. |
| تدمد: | 1661-7819 1661-7800 |
| DOI: | 10.1159/000518687 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::a734f8fa2fd35bfe865a4a019af463c5 https://doi.org/10.1159/000518687 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........a734f8fa2fd35bfe865a4a019af463c5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16617819 16617800 |
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| DOI: | 10.1159/000518687 |