Retrospective Evaluation of the Bifractionated Scheme in Utero-Vaginal Brachytherapy in the Treatment of Cervical Cancer : Experience of the Radiotherapy Oncology Service at Marrakech University Hospital
| العنوان: | Retrospective Evaluation of the Bifractionated Scheme in Utero-Vaginal Brachytherapy in the Treatment of Cervical Cancer : Experience of the Radiotherapy Oncology Service at Marrakech University Hospital |
|---|---|
| المؤلفون: | M Elanigri, Bouchabaka Y, H Abourrazek, I Lalya, M. Khouchani, A. Elomrani, A Zayane |
| المصدر: | Tumori Journal. 106:2-2 |
| بيانات النشر: | SAGE Publications, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Cervical cancer, Service (business), Cancer Research, medicine.medical_specialty, business.industry, medicine.medical_treatment, General Medicine, University hospital, medicine.disease, High-Dose Rate Brachytherapy, Radiation therapy, Oncology, In utero, Vaginal brachytherapy, Medicine, Radiology, business |
| الوصف: | Objective: To retrospectively report the results in terms of local control and toxicities, of the 2 x 9 Gy fractionation used in our service, in high dose rate brachytherapy, during the treatment of locally advanced cervical cancer, preceded by a concomitant chemotherapy radiotherapy association. Material and method: Report and analyze data from 106 patients treated in our center between 2015 and 2018, for cervical cancer stage IIB and IIIB according to the FIGO classification. Results: The median follow-up was 29 months. Among the 106 patients analyzed, 75.5% had good local control at 3 years against 7.5% who had local progression, while 9.5% had local relapse and 7.5% had metastatic relapse. The average time for the occurrence of an event (progression, local or remote relapse) was 8 months. Most patients (90.6%) did not have acute toxicity. As for chronic toxicities, 66% had good long-term tolerance, while 27.4% had synechiae or even vaginal stenosis. The other toxicities were in the minority. Conclusion: Despite the considerable advantage of 2 x 9 Gy fractionation in uterovaginal brachytherapy in terms of reduction in treatment time, it is not the ideal choice in terms of local control and toxicity and the 3 x 8 Gy scheme seems a good alternative. |
| تدمد: | 2038-2529 0300-8916 |
| DOI: | 10.1177/0300891620914118 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::a2160304deefa6b32e065834891a5326 https://doi.org/10.1177/0300891620914118 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........a2160304deefa6b32e065834891a5326 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20382529 03008916 |
|---|---|
| DOI: | 10.1177/0300891620914118 |