Screening of the ability of natural feed ingredients commonly used in pig diets to interfere with the attachment of ETEC K88 (F4) to intestinal epithelial cells
التفاصيل البيبلوغرافية
العنوان:
Screening of the ability of natural feed ingredients commonly used in pig diets to interfere with the attachment of ETEC K88 (F4) to intestinal epithelial cells
Enterotoxigenic Escherichia coli (ETEC) K88 (F4) is a worldwide cause of severe diarrhoea in the offspring of some animal species such as weaned pigs. Preventing ETEC K88 (F4) attaching to the small intestine by natural feed ingredients interfering with its fimbria-receptor recognition could be an alternative method to reduce diarrhoea occurrence. The purpose of this study is to evaluate the ability of different common ingredients in the formulation of pig diets, and particularly different kinds of cereal brans, to attach ETEC K88 (F4) (adhesion test, AT) and to block its attaching to intestinal epithelial cells (IPEC-J2) (blocking test, BT) in vitro. For the feed ingredients, wheat, corn, oats, barley, rye, extruded full-fat soybean meal, soybean meal, as well as sweet whey powder, all demonstrated a clear affinity to attach ETEC K88 (F4) (P