Cu-Catalyzed Asymmetric Aminoboration of E-Vinylarenes with pivZPhos as the Ligand
| العنوان: | Cu-Catalyzed Asymmetric Aminoboration of E-Vinylarenes with pivZPhos as the Ligand |
|---|---|
| المؤلفون: | Linglin Wu, Lucille A. Wells, Bo Qu, Olga V. Zatolochnaya, Jinhua J. Song, Yongda Zhang, Marisa C. Kozlowski, Ling Wu, Chris H. Senanayake |
| المصدر: | Organic Letters. 21:8952-8956 |
| بيانات النشر: | American Chemical Society (ACS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 010405 organic chemistry, Chemistry, Extramural, Stereochemistry, Ligand, Organic Chemistry, Enantioselective synthesis, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, Catalysis, Adduct, chemistry.chemical_compound, Oxazepine, Computational analysis, Physical and Theoretical Chemistry |
| الوصف: | A Cu-catalyzed enantioselective aminoboration of E-vinylarenes with pivZPhos as a ligand is reported. Enantioenriched aminoborates are prepared with excellent regio- and enantioselectivities up to >99:1 er under the optimized conditions. The utility of the current method was further established by rapid conversion of an adduct to a chiral benzo[f][1,4]oxazepine. A model for the stereochemistry of the asymmetric aminoboration process, which agrees with the experimental outcomes, was generated by computational analysis of the systems. |
| تدمد: | 1523-7052 1523-7060 |
| DOI: | 10.1021/acs.orglett.9b03328 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::9c0c25363a1d7049e56cc3623cca5ee8 https://doi.org/10.1021/acs.orglett.9b03328 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........9c0c25363a1d7049e56cc3623cca5ee8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15237052 15237060 |
|---|---|
| DOI: | 10.1021/acs.orglett.9b03328 |