Sleep deprivation alters neutrophil functions and levels of Th1-related chemokines and CD4+ T cells in the blood
| العنوان: | Sleep deprivation alters neutrophil functions and levels of Th1-related chemokines and CD4+ T cells in the blood |
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| المؤلفون: | Elias A. Said, Mohamed A. Idris, Mohammed A. Al-Abri, Ali A. Al-Jabri, Mohammed S. Al-Balushi, Omar Habbal, Crystal Y. Koh, Iman Al-Saidi, J.Z. Al-Busaidi, Iman Al-Reesi |
| المصدر: | Sleep and Breathing. 23:1331-1339 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Chemokine, medicine.medical_specialty, NADPH oxidase, biology, business.industry, T cell, CCL5, 03 medical and health sciences, Sleep deprivation, 0302 clinical medicine, medicine.anatomical_structure, Immune system, Endocrinology, 030228 respiratory system, Otorhinolaryngology, Internal medicine, biology.protein, Medicine, CXCL10, CXCL9, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery |
| الوصف: | The state of knowledge about the effect of sleep deprivation on the immune system is scarce and conflicting. It would therefore be useful to investigate the consequences of sleep deprivation on the immune system. We have studied the effect of sleep deprivation on the changes in neutrophil functions, and the ex vivo proliferative pattern of CD4+ T lymphocytes in relationship with blood cytokine and chemokine levels due to the crucial role of these cells in mounting potent immune responses. Healthy volunteers were followed for 3 weeks. They had normal sleep in weeks 1 and 3 and they were sleep-deprived on week 2, sleeping |
| تدمد: | 1522-1709 1520-9512 |
| DOI: | 10.1007/s11325-019-01851-1 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::96f93c4ec0a37e4737f308bb1dc24fdb https://doi.org/10.1007/s11325-019-01851-1 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........96f93c4ec0a37e4737f308bb1dc24fdb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15221709 15209512 |
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| DOI: | 10.1007/s11325-019-01851-1 |