Interaction Between Oxytocin and Opioidergic System on Food Intake Regulation in Neonatal Layer Type Chicken
| العنوان: | Interaction Between Oxytocin and Opioidergic System on Food Intake Regulation in Neonatal Layer Type Chicken |
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| المؤلفون: | B Vazir, Ahmad Asghari, Negar Panahi, Morteza Zendehdel, Faramarz Raji-Dahmardeh |
| المصدر: | International Journal of Peptide Research and Therapeutics. 26:1905-1912 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Opioidergic, Agonist, medicine.medical_specialty, 010405 organic chemistry, medicine.drug_class, Antagonist, Bioengineering, Receptor antagonist, 01 natural sciences, Biochemistry, Oxytocin Antagonist, 0104 chemical sciences, Analytical Chemistry, DAMGO, chemistry.chemical_compound, Endocrinology, chemistry, Oxytocin, Internal medicine, Drug Discovery, medicine, Molecular Medicine, Receptor, hormones, hormone substitutes, and hormone antagonists, medicine.drug |
| الوصف: | The aim of the current study was to determine possible interaction of central oxytocin and opioidergic system on food intake regulation in neonatal layer-type chicken. In experiment 1, FD3 chicken ICV injected with control solution, oxytocin (10 µg), β-FNA (µ receptor antagonist, 5 µg) and oxytocin (10 µg) + β-FNA were injected. Experiments 2–6 were similar to experiments 1, except chicken injected with nor-BNI (κ receptor antagonist, 5 µg), NTI (δ receptor antagonist, 5 µg), DAMGO (µ receptor agonist, 62.25 pmol), U-50488H (κ receptor agonist, 10 nmol), DPDPE (δ receptor agonist, 20 pmol) instead of β-FNA. In experiment 7, control solution, DAMGO (125 pmol), d(CH2)5Tyr(Me)-[Orn8]-vasotocin (oxytocin antagonist, 5 µg) and DAMGO + d(CH2)5Tyr(Me)-[Orn8]-vasotocin were ICV injected to FD3 chicken. Experiments 8 and 9 were similar to experiments 7, except chicken injected with U-50488H (30 nmol) and DPDPE (40 pmol) instead of DAMGO. Then, cumulative food intake was recorded at 30, 60 and 120 min after injection. According to the results, ICV injection of the oxytocin (10 µg) significantly decreased food intake compared to control group (P |
| تدمد: | 1573-3904 1573-3149 |
| DOI: | 10.1007/s10989-019-09944-x |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::91b4cb9c8d6d00b95f82940a8b19d9bd https://doi.org/10.1007/s10989-019-09944-x |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........91b4cb9c8d6d00b95f82940a8b19d9bd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15733904 15733149 |
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| DOI: | 10.1007/s10989-019-09944-x |