Radiation dermatitis: the evaluation of a new topical therapy for the treatment and prevention of radiation-induced skin damage and moist desquamation: a multicentre UK case cohort study
| العنوان: | Radiation dermatitis: the evaluation of a new topical therapy for the treatment and prevention of radiation-induced skin damage and moist desquamation: a multicentre UK case cohort study |
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| المؤلفون: | G. Fenton, R. J. White, K. Johnson |
| المصدر: | Journal of Radiotherapy in Practice. 20:461-465 |
| بيانات النشر: | Cambridge University Press (CUP), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, 030504 nursing, business.industry, Radiation induced, Dermatology, 03 medical and health sciences, 0302 clinical medicine, Moist desquamation, Oncology, 030220 oncology & carcinogenesis, medicine, Radiology, Nuclear Medicine and imaging, 0305 other medical science, business, Cohort study, Skin damage |
| الوصف: | Introduction:Radiotherapy is a mainstay of cancer therapy for a wide variety of anatomical areas. An unfortunate side effect of treatment can be radiation damage to the skin which can be a painful and debilitating problem. Previous experience from the experimental use of Flamigel® in two large-scale clinical studies on affected skin has proven sufficiently positive for the addition of a new product in the Flamigel® family (now commercially available in the UK as Flamigel RT®, Flen Health UK). The aim of this investigation is to evaluate the use of this new product to study how effective it is in the prevention and/or treatment of radiation-induced skin damage.Materials and methods:A survey was conducted among radiotherapy specialist teams in dedicated UK radiotherapy centres between 1 January 2017 and 31 October 2017. This report is of a preliminary evaluation conducted by UK-based specialists on 108 patients undergoing radiotherapy. The scoring system for skin reactions of the ‘Radiation Therapy Oncology Group’ was used.Results:Results show that the use of Flamigel® has the potential to soothe (p = 0·0001), reduce pain (p = 0·0001) and reduce pruritus (p = 0·004). The product met the expectations of the clinicians involved (p < 0·0001) of whom most were happy to continue use or to recommend its use to colleagues (p < 0·0001).Conclusions:Flamigel® is an effective treatment in the management of radiation-induced skin reactions. Erythema was unchanged through the study period (p = 0·42). No adverse reactions were reported after the use of Flamigel from twice to six times a day. |
| تدمد: | 1467-1131 1460-3969 |
| DOI: | 10.1017/s1460396920001077 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::8f4438d16cf1d3b4d894cb899564d670 https://doi.org/10.1017/s1460396920001077 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........8f4438d16cf1d3b4d894cb899564d670 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14671131 14603969 |
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| DOI: | 10.1017/s1460396920001077 |