Abstract 65: Anemia-related Heart Failure in Sub-saharan African Sickle Cell Disease Patients
| العنوان: | Abstract 65: Anemia-related Heart Failure in Sub-saharan African Sickle Cell Disease Patients |
|---|---|
| المؤلفون: | Yahya Aliyu, AA Babadoko, Adebayo Atanda, Aisha Indo Mamman, Oluwafunmilayo Atanda, Zakari Y. Aliyu, Aisha Suleiman |
| المصدر: | Circulation Research. 121 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, Sub saharan, Physiology, Anemia, business.industry, Cell, Disease, medicine.disease, medicine.anatomical_structure, Heart failure, Internal medicine, medicine, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Introduction: Anemia has been implicated in heart failure. Existing literatures, involving predominantly African-Americans, suggests that Sickle Cell Disease (SCD) maybe linked to various cardiovascular complications including pulmonary hypertension and left venticular dysfunction. Peculiarly, our study involves exclusively Sub-Saharan population. Method: We conducted a cross sectional observational study of 208 hydroxyurea-naive consecutive SCD patients aged 10-52 years at steady state and 94 healthy non-matched controls who were studied in an out patient clinic in Sub-Saharan Africa. SCD patients were required to have electrophoretic or liquid chromatography documentation of major sickling phenotypes. Control group was required to have non-sickling phenotypes. Cardiac measurements were performed with TransThoracic Echo according to American Society of Echocardiography guidelines. Hemoglobin level was also obtained. Results: Hemoglobin level in SCD group (8.5+/- 1.5) was significant (P Conclusions: We were unable to demonstrate existence of anemia-associated left ventricular dysfunction in Sub-Saharan African with SCD. Further studies is required to highlight the reason behind this finding. |
| تدمد: | 1524-4571 0009-7330 |
| DOI: | 10.1161/res.121.suppl_1.65 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::8d9973392d04d9b21a8ccf19a57cbdbd https://doi.org/10.1161/res.121.suppl_1.65 |
| رقم الانضمام: | edsair.doi...........8d9973392d04d9b21a8ccf19a57cbdbd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244571 00097330 |
|---|---|
| DOI: | 10.1161/res.121.suppl_1.65 |