Application of α-Amino-β-fluorophosphonates in Construction of their Dipeptide Analogues
| العنوان: | Application of α-Amino-β-fluorophosphonates in Construction of their Dipeptide Analogues |
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| المؤلفون: | Tomasz Cytlak, Grzegorz Dutkiewicz, Marcin Kaźmierczak |
| المصدر: | Synthesis. 52:2364-2372 |
| بيانات النشر: | Georg Thieme Verlag KG, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Dipeptide, 010405 organic chemistry, Stereochemistry, Chemistry, Phosphorus, Organic Chemistry, Absolute configuration, Hexacoordinate, chemistry.chemical_element, 010402 general chemistry, 01 natural sciences, Catalysis, 0104 chemical sciences, Ion formation, chemistry.chemical_compound, Fluorine |
| الوصف: | Herein, we present application of α-amino-β-fluorophosphonates for the construction of their dipeptide analogues. α-Amino-β-fluorophosphonates were prepared in a XtalFluor-E mediated deoxyfluorination of α-hydroxy-β-aminophosphonates. The reaction proceeds through an aziridinium ion formation, which was confirmed by the formation of a hexacoordinate phosphorus compound. Moreover, the absolute configuration of the obtained compounds was determined by X-ray analysis, which proved the stereochemistry. |
| تدمد: | 1437-210X 0039-7881 |
| DOI: | 10.1055/s-0040-1707813 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::84c67dc133e9a8b9af7f5afd30c5a9b1 https://doi.org/10.1055/s-0040-1707813 |
| رقم الانضمام: | edsair.doi...........84c67dc133e9a8b9af7f5afd30c5a9b1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1437210X 00397881 |
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| DOI: | 10.1055/s-0040-1707813 |