ANTIMICROBIAL, ANTIOXIDANT ACTIVITY, AND CHEMICAL COMPOSITION OF ORIGANUM COMPACTUM BENTH FROM TAOUNATE PROVINCE, NORTH MOROCCO
| العنوان: | ANTIMICROBIAL, ANTIOXIDANT ACTIVITY, AND CHEMICAL COMPOSITION OF ORIGANUM COMPACTUM BENTH FROM TAOUNATE PROVINCE, NORTH MOROCCO |
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| المؤلفون: | Mahdi Chaouch, Noureddine Eloutassi, Abdellah Chaqroune, Ahmed Zeroual |
| المصدر: | Asian Journal of Pharmaceutical and Clinical Research. :126-131 |
| بيانات النشر: | Innovare Academic Sciences Pvt Ltd, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Pharmacology, Antioxidant, Traditional medicine, medicine.medical_treatment, medicine, Pharmaceutical Science, Pharmacology (medical), Biology, Antimicrobial, Chemical composition, Origanum compactum |
| الوصف: | Objective: Origanum compactum is one of the most important medicinal species in terms of ethnobotany in Morocco. It attracts the attention of several research works; however, its chemical composition under local conditions is not well documented. Here, we aimed at determining essential oil chemical composition, antibacterial, and antioxidant activities of organic extracts of O. compactum. Methods: Antimicrobial activities were assessed against four strains (Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Candida albicans). Antioxidant activities were estimated by radical 2,2-diphenyl-1-picrylhydrazyl scavenging activity. Polyphenols and flavonoids were determined. Chemical composition was screened using gas chromatography. Results: Our results showed that yield extracts varied significantly among solvents and ranged from 10.30% (n-hexane) to 31.70% (methanolic). Methanolic extracts had the highest values of yield, polyphenols, and flavonoids, while n-hexane extracts showed the lowest values of yield and polyphenols. Regarding antimicrobial activities, E. coli showed the most important activity. Concerning antioxidant activities, n-hexane extracts had the most important activity. The phytochemical screening revealed 12 compounds. Among them, γ-Terpinene, o-Cymene, and carvacrol were the major compounds (around 73% of total chemical compounds). Conclusion: It could be concluded that the studied plant might be a promising source of chemical compounds responsible for important biological activities. |
| تدمد: | 2455-3891 0974-2441 |
| DOI: | 10.22159/ajpcr.2020.v13i3.36319 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::83671fb80561bc966b5573cc06a725c2 https://doi.org/10.22159/ajpcr.2020.v13i3.36319 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........83671fb80561bc966b5573cc06a725c2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 24553891 09742441 |
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| DOI: | 10.22159/ajpcr.2020.v13i3.36319 |