Scalable On-Demand Production of Purified Diazomethane Suitable for Sensitive Catalytic Reactions
| العنوان: | Scalable On-Demand Production of Purified Diazomethane Suitable for Sensitive Catalytic Reactions |
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| المؤلفون: | Anamika Datta, Matthew M. Bio, Changfeng Huang, Scott J. Hecker, Serge H. Boyer, Jillian W. Sheeran, Yuan-Qing Fang, M. Grace Russell, David D. Ford, Kiersten Campbell, Gerald Hummel, Christopher P. Breen |
| المصدر: | Organic Process Research & Development. 25:522-528 |
| بيانات النشر: | American Chemical Society (ACS), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 010405 organic chemistry, Chemistry, Cyclopropanation, Diazomethane, Organic Chemistry, Continuous manufacturing, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Catalysis, chemistry.chemical_compound, On demand, Yield (chemistry), Organic chemistry, Physical and Theoretical Chemistry, Plug flow reactor model |
| الوصف: | We have developed a convenient development-scale reactor (0.44 mol/h) to prepare diazomethane from N-methyl-N-nitroso-p-toluenesulfonamide (MNTS) in ∼80% yield. Diazomethane (CH2N2) made with this ... |
| تدمد: | 1520-586X 1083-6160 |
| DOI: | 10.1021/acs.oprd.0c00485 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::8076cc651bf6101bd3bad5eefab930e2 https://doi.org/10.1021/acs.oprd.0c00485 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........8076cc651bf6101bd3bad5eefab930e2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1520586X 10836160 |
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| DOI: | 10.1021/acs.oprd.0c00485 |